Children’s Health

Scientists from Israel have recently explored the effectiveness of two-dose and three-dose regimens of the BNT162b2 coronavirus disease 2019 (COVID-19) vaccine (Pfizer/BioNTech) to reduce viral load in breakthrough infections caused by the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Furthermore, they observe that the gradual reduction of vaccine efficacy against viral load
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Licensing productive transcription through RNA polymerase II stabilityPlay Video Credit: Northwestern University Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell. According to the study, the presence of a protein called SPT5 serves as a “passport,” determining
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The four Chief Medical Officers will provide further advice on the COVID-19 vaccination of young people aged 12 to 15 with COVID-19 vaccines following the advice of the independent Joint Committee on Vaccination and Immunisation (JCVI). The independent medicines regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), has approved the Pfizer and Moderna vaccines
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With an average accuracy of 88%, a deep learning technology offers rapid genetic screening that could accelerate the diagnosis of genetic syndromes, recommending further investigation or referral to a specialist in seconds, according to a study published in The Lancet Digital Health. Trained with data from 2,800 pediatric patients from 28 countries, the technology also
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From tele-monitoring patients with diabetes to using artificial intelligence to prevent sepsis, the newly launched Center for Health Innovation at UC San Diego Health will seek to develop, test and commercialize technologies that make a real, measurable difference in the lives and wellbeing of patients. Every U.S. hospital has common challenges to address in continuously
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A new study by researchers at Winship Cancer Institute of Emory University finds that cancer-associated mutations originate in blood progenitor cells, leading to distinct changes in both cancer and non-cancer immune cells in Waldenstrom macroglobulinemia (WM), a type of non-Hodgkin lymphoma and its precursor IgM monoclonal gammopathy of undetermined significance (MGUS). The study by Madhav.
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Researchers from Children’s Hospital of Philadelphia (CHOP) have found that children on the autism spectrum who have impaired executive functioning skills, which help control thoughts, emotions, and actions, can face challenges at school that are different from the ones they face at home. Additionally, as children experience adolescence, problems with executive functioning can worsen, suggesting
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Studies have determined that in-school transmission of the virus that causes COVID-19 is rare when masking, social distancing and other safety protocols are followed. However, little has been known about COVID-19 risks at school for children with intellectual and developmental disabilities. These students often are unable to mask or maintain social distancing and may have
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David Sela, a nutrition scientist at the University of Massachusetts Amherst, has received a five-year, $1.69 million grant from the National Institutes of Health (NIH) to investigate how nitrogen in human milk is used by beneficial microbes in the infant gut to potentially play an important role in pediatric nutrition and development. The new experiments,
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The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19. Although most patients improve with medical care, more than half the MIS-C cases in the U.S. require ICU admission, and the condition can be deadly. A
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A new study from the Prevention Research Center of the Pacific Institute for Research and Evaluation finds that recreational marijuana legalization may increase the risk of alcohol and marijuana co-use among adolescents. The study examined the association between recreational marijuana legalization in California in November 2016 and alcohol and marijuana co-use among underage youth. The
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Northwestern Medicine scientists continue to investigate all aspects of the COVID-19 pandemic: from molecular mechanisms of infection, to child hospitalization and single-dose vaccine response. One dose not enough for previously infected Thomas McDade, PhD, professor of Medical Social Sciences, was senior author of the study published in EClinical Medicine. One dose of an mRNA vaccine
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A deep look into a nationwide mass vaccination setting in Israel revealed that the BNT162b2 (Pfizer–BioNTech) vaccine is not linked with an elevated risk of a majority of the adverse events under study, with the exception of myocarditis. However, even that potentially severe adverse event is much more pervasive following the infection with severe acute
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Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment
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Researchers from the HSE Centre for Language and Brain and their Russian and American colleagues have become the first to compare expressive and receptive language abilities of Russian children with Autism Spectrum Disorder (ASD) at different linguistic levels. Their work helped them refute the hypothesis that children with ASD understand spoken language less well than
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Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations. This finding opens up a new
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The side effects of the Pfizer-BioNTech jab against COVID-19 are likely to be mild to moderate and clear up quickly in 12-15 year olds at high risk of complications from the infection because of certain coexisting conditions, reveals a small study accepted for publication in the Archives of Disease in Childhood. Although the study numbers
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